메뉴 건너뛰기

XEDITION

Board

Class="nodetitle">Viagra

ZWZSylvia20037274 2026.01.08 09:00 조회 수 : 1

Viagra is a drug used to treat male erectile dysfunction, developed by the pharmaceutical company Pfizer.
The generic name for this compound is ''sildenafil''. It is a blue pill with the words "Pfizer" on one side and "VGR xx" (with xx being either 25, 비아그라 구입 50 or 100 as the miligram dose of that pill) on the other. Chemical name: 1-[4-ethoxy- 3-(6,7-dihydro- 1-methyl- 7-oxo- 3-propyl- 1H-pyrazolo [4,3-d]pyrimidin-5-yl) phenylsulfonyl]- 4-methylpiperazine citrate.
Molecular formula: C22H30N6O4S.C6H807. MW: 666.7 Mechanism of action

Part of the physiological process of erection involves the release of nitric oxide (NO) in the corpus cavernosum. This then activates the enzyme, guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP) which results in smooth muscle relaxation in the corpus cavernosum which leads to increased inflow of blood which leads directly to erection. Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum.

This means that, with Viagra on board, normal sexual stimulation leads to increased levels of cGMP in the corpus cavernosum which leads to better erections. Without sexual stimulation and no activation of the NO/cGMP system, Viagra should not cause an erection. Contraindications
- when taking other nitric oxide donors, organic nitrites and nitrates (which includes glyceryl trinitrate, sodium nitroprusside, amyl nitrite)
- in men for whom sexual intercourse is inadvisable due to cardiovascular risk factors

- severe hepatic impairment
- severe impairment in renal function
- hypotension
- recent stroke or heart attack (myocardial infarct)
- hereditary degenerative retinal disorders (including genetic disorders of retinal phosphodiesterases) Dose
The dose of viagra is 50mg to 100mg taken once per day between 0.5 to 4 hours before sexual intercourse. If taken with a high fat meal, there may be a delay in absorbtion of Viagra and the net effect might be muted slightly as the plasma concentration will be lowered.

Adverse effects
Amongst viagra's serious adverse effects are: priapism, severe hypotension, myocardial infarction, ventricular arrhythmias, sudden death, stroke and increased intraocular pressure. Common side effects include headache, flushing, dyspepsia, prolonged erections, palpitations and photophobia.
Temporary visual changes including blurring of vision and a curious bluish tinge have also been reported. Metabolism and excretion
Viagra is metabolised by hepatic enzymes and excreted by both the liver and kidneys.

Is it any coincidence that the choice of virtual reality over reality in The Matrix is a blue pill?

번호 제목 글쓴이 날짜 조회 수
66582 10 Pieces Of League Of Legends Fan Art That We Love BenedictHecht63665221 2026.01.10 2
66581 The Most Effective Organic Skincare Travel Dimension 2024 DoreenVux94224211512 2026.01.10 2
66580 How London Locksmith Can Assist You ClaudetteWells5189 2026.01.10 4
66579 FYREBX T5 Western Fire Supply ShonaFunderburk60 2026.01.10 2
66578 How G2 Took Over The LEC MitchellKomine722 2026.01.10 5
66577 ลิเวอร์พูล Allison9767474408843 2026.01.10 12
66576 4 Incredible Free Slots Double Diamond Examples JanineSpell66953511 2026.01.10 2
66575 League Of Legends Patch 10.6 Notes - New Lux Skins And More! Sherlene6412983 2026.01.10 0
66574 Superhero Movie Quotes Nobody Talks About FlorianBostick98546 2026.01.10 1
66573 Make Cash Money For Surveys By Using Free Paid Online Surveys LinneaV838739818735 2026.01.10 4
66572 Things You Need To Know About A Locksmith VDHCandy2499773354054 2026.01.10 2
66571 Casino Slots Win Rate Strategies Revealed TeshaJohnstone1875 2026.01.10 3
66570 How To Maximize Free Spins On Thai Mobile Slot Apps BlytheChristenson 2026.01.10 2
66569 A Secret Weapon For Access Control DustinKunz4496274383 2026.01.10 4
66568 If It Functions For Anti, Professionals Reveal TammyMckeever90586161 2026.01.10 5
66567 3D Rendering Company, New York DeannaFewings48796 2026.01.10 2
66566 How London Locksmith Can Assist You DonnellL0002431441803 2026.01.10 4
66565 Exactly How To Outmaneuver Your Peers On Best Areas For Children Celebrations GiaEngel2488064 2026.01.10 2
66564 แมนยู SoonMcmullen699262 2026.01.10 11
66563 Find The Very Best Advertising Agencies BillGlenn88719115672 2026.01.10 3
위로