메뉴 건너뛰기

XEDITION

Board

Class="nodetitle">Viagra

ZWZSylvia20037274 2026.01.08 09:00 조회 수 : 1

Viagra is a drug used to treat male erectile dysfunction, developed by the pharmaceutical company Pfizer.
The generic name for this compound is ''sildenafil''. It is a blue pill with the words "Pfizer" on one side and "VGR xx" (with xx being either 25, 비아그라 구입 50 or 100 as the miligram dose of that pill) on the other. Chemical name: 1-[4-ethoxy- 3-(6,7-dihydro- 1-methyl- 7-oxo- 3-propyl- 1H-pyrazolo [4,3-d]pyrimidin-5-yl) phenylsulfonyl]- 4-methylpiperazine citrate.
Molecular formula: C22H30N6O4S.C6H807. MW: 666.7 Mechanism of action

Part of the physiological process of erection involves the release of nitric oxide (NO) in the corpus cavernosum. This then activates the enzyme, guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP) which results in smooth muscle relaxation in the corpus cavernosum which leads to increased inflow of blood which leads directly to erection. Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum.

This means that, with Viagra on board, normal sexual stimulation leads to increased levels of cGMP in the corpus cavernosum which leads to better erections. Without sexual stimulation and no activation of the NO/cGMP system, Viagra should not cause an erection. Contraindications
- when taking other nitric oxide donors, organic nitrites and nitrates (which includes glyceryl trinitrate, sodium nitroprusside, amyl nitrite)
- in men for whom sexual intercourse is inadvisable due to cardiovascular risk factors

- severe hepatic impairment
- severe impairment in renal function
- hypotension
- recent stroke or heart attack (myocardial infarct)
- hereditary degenerative retinal disorders (including genetic disorders of retinal phosphodiesterases) Dose
The dose of viagra is 50mg to 100mg taken once per day between 0.5 to 4 hours before sexual intercourse. If taken with a high fat meal, there may be a delay in absorbtion of Viagra and the net effect might be muted slightly as the plasma concentration will be lowered.

Adverse effects
Amongst viagra's serious adverse effects are: priapism, severe hypotension, myocardial infarction, ventricular arrhythmias, sudden death, stroke and increased intraocular pressure. Common side effects include headache, flushing, dyspepsia, prolonged erections, palpitations and photophobia.
Temporary visual changes including blurring of vision and a curious bluish tinge have also been reported. Metabolism and excretion
Viagra is metabolised by hepatic enzymes and excreted by both the liver and kidneys.

Is it any coincidence that the choice of virtual reality over reality in The Matrix is a blue pill?

번호 제목 글쓴이 날짜 조회 수
59793 The Best Organic Skin Care Traveling Size 2024 Nick54383630140 2026.01.09 1
59792 5 No Cost Ways To Get More With Vape With No Nicotine RandyLafountain16547 2026.01.09 2
59791 Diyarbakır Escort Hatunların Adresi Ve Özellikleri BlancheKiley88530376 2026.01.09 9
59790 3D Making Services By Architectural Visualization Workshop FORTES.VISION. KentonAguirre72 2026.01.09 2
59789 Karen Lynn Brady SarahWhaley107604 2026.01.09 0
59788 Xxx TeraMolineux284 2026.01.09 0
59787 Xxx MargoOcasio5619721 2026.01.09 0
59786 Citadel Expands Search Engine Optimization Provider For Plastic Surgeons DonteHerrera013 2026.01.09 2
59785 United States JorjaCookson851970866 2026.01.09 3
59784 Get In Touch With. BrandenNarvaez300 2026.01.09 2
59783 Get Lucky Fast With Thailand’S Hottest Mobile Slots ErnaLillibridge357 2026.01.09 3
59782 Diyarbakır Escort - Diyarbakır Onaylı Escort - Diyarbakır Vip Elit Bayan BlancheKiley88530376 2026.01.09 1
59781 Digital Advertising And Marketing Solutions SarahAckerman261408 2026.01.09 2
59780 Xxx JocelynStclair107 2026.01.09 0
59779 Advanced Tricks For Winning Thai Mobile Slot Players LynetteGrills971 2026.01.09 2
59778 Beş Yıl Önce LowellRhoden319541 2026.01.09 5
59777 Vape Clearance Sale FloridaSosa516489 2026.01.09 1
59776 Copper Peptide GHK RaymonTenney2309 2026.01.09 0
59775 3D Outside Making Providers EstelleIves095268 2026.01.09 2
59774 Gallon Firefighting Add-on Established For Skid Steer Loader Alta9096603509113377 2026.01.09 3
위로